Epigenetics Market is anticipated to value over USD 4 billion by 2027 end with a CAGR of over 12% during the forecast period 2020 to 2027.
Epigenetic changes are responsible for human diseases, including Fragile X syndrome, Angelman's syndrome, Prader-Willi syndrome, and various cancers. Epigenetic changes alter the physical structure of DNA. One example of an epigenetic change is DNA methylation the addition of a methyl group, or a "chemical cap," to part of the DNA molecule, which prevents certain genes from being expressed. Another example is histone modification.
Major players in epigenetics market are Thermo Fisher Scientific, Inc., Illumina, Inc., Novartis AG, Hoffmann-La Roche Ltd., and Eisai Co. Ltd.
The recent analyses of epigenetic modifications in allergic disease is recently attracted towards the environment of the protection from allergic disease as well as constitute a novel class of biomarkers and provides new therapeutic targets. The new article of Thermo Fisher Scientific, Inc., in 2020 said that The ability of PRMTs to catalyze arginine methylation results in changes in protein-protein interactions involved in biological processes such as cell signaling, cell differentiation, DNA repair, mRNA splicing, transcription, mRNA translation, and embryonic development. The main substrates of PRMTs are histones leading to their foremost role in the epigenetic regulation of gene expression. They methylate key activating and repressive histone marks. Mutations in PRMT genes leading to cancer are rare, but their expression is often unregulated in cancer and associated with poor patient prognosis.
Lead by Raffaella Nativio, PhD, a former research associate of Epigenetics, Shelley Berger, PhD, a professor of Genetics, Biology and Cell and Developmental Biology used post-mortem brain tissue to compare healthy younger and older brain cells to those with Alzheimer's disease. The team found evidence that epigenetic regulators disable protective pathways and enable pro-disease pathways in those with the disease. According to WHO, Asthma is a worldwide disease with more than 230 million people affected across all races and continents. In epigenetics several large scale epigenome wide association studies (EWAS) has been published and recent focused on the interaction between external and internal environment and epigenetics signatures our knowledge to novel environmental factors and mechanism of disease.
Global epigenetics market segmentation, by product: Reagents, Kits, Instruments, and Enzymes. Global epigenetics market segmentation, by technology: DNA Methylation, Histone Modifications, and RNA-Associated Silencing. Global epigenetics market segmentation, by application: Oncology, Solid Tumors, Liquid Tumors, Non Oncology, Cardiovascular diseases, Infectious diseases, inflammatory disease, and metabolic diseases. Global epigenetics market segmentation, by end user: Academic and Research Institutes, Pharmaceutical and Biotechnology Companies, Contract Research Organizations. By region it segmented into North America (the U.S, Canada), Latin America (Brazil, Peru, Mexico, Chile, and others), Western Europe (Germany, Italy, Nordic countries, Belgium, U.K., France, Spain, Netherlands, and Luxembourg), Eastern Europe (Poland and Russia) and Asia Pacific.
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